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LAMEP

Plant Metabolism Laboratory

Institute of Biosciences - São Paulo State University (UNESP) Logo IBCLP
Discover Our Research

About LAMEP

LAMEP: Decoding Photosynthetic Resilience in a Changing World

The future of sustainability and climate depends on one major question: how will photosynthetic organisms survive Earth's new climate? At the Plant Metabolism Laboratory (LAMEP), we investigate the resilience of life — from forests and crops to the immense biodiversity of oceans and aquatic ecosystems.

Our research dives beyond terrestrial plants. At LAMEP, we focus on the crucial role of macro and microalgae. These organisms are fundamental biological engines for climate regulation and the new bioeconomy. By integrating the study of plant metabolism with algal physiology, we seek strategies to protect food production and explore the biotechnological potential of these "lungs" of the planet.

Our Innovation Pillars:

  • Comparative Physiology: We analyze how plants, macro, and microalgae respond to extremes of temperature, drought, and salinity.
  • Bioinspiration and Algae: We explore the high plasticity of algae and native flora to discover adaptation mechanisms applicable to agriculture and environmental conservation.
  • Nanotechnology: We apply cutting-edge solutions to increase efficiency and stress tolerance across the entire photosynthetic spectrum.

Research Projects

Ongoing

Evaluation of photoprotective mechanisms and memory effect in soybean cultivars under recurrent drought (FAPESP 2024/21237-3)

Investigation of how prior exposure to moderate drought in early developmental stages optimizes soybean tolerance to subsequent drought events.

Soybean Climate Change Drought
Ongoing / Collaboration

Evaluating adaptation, epigenetic variation, and dispersal to understand mangrove responses (FAPESP 2022/02804-9)

Evaluating the contribution of ocean currents and investigating genetic, epigenetic, and phenotypic variation in persistence under new environmental conditions.

Molecular Ecology Mangroves
Ongoing

Regulation of Electron Transport and Photoprotective Mechanisms to Increase Photosynthetic Efficiency (CNPQ 301453/2022-5)

Evaluation of the role of photosystem photoinhibition (PSII and PSI) and its photoprotective mechanisms for increasing photosynthetic efficiency.

Photosynthesis Photoprotection
Ongoing

Using mycogenic nanoparticles as bio-inputs for protection against abiotic stresses

Investigation of the potential of mycogenic nanoparticles as biostimulants to protect plants and algae against drought, salinity, and high temperatures.

Nanomaterials Bio-inputs
Ongoing

Environmental Biotechnology: Bio-inputs from Aquaculture Waste Reuse

Development of integrated production systems that promote the bioremediation of wastewater, transforming environmental liabilities into productive resources.

Circular Bioeconomy Bioremediation
Ongoing / Collaboration

Diffusive and metabolic modulation of CAM photosynthesis in Agave under salinity

We seek to understand how Agave plants, considered obligate CAM, modulate the regulation of key CAM cycle enzymes (such as Rubisco and PEPcase) and stomatal diffusive behavior in response to salt stress.

Photosynthesis CAM Metabolism Salt Stress Climate Change
Ongoing

Outreach Project: Seeing Green: Tools and strategies to mitigate plant blindness

Scientific literacy actions aimed at diagnosing and mitigating Plant Blindness among teachers, students, and the general public.

Plant Blindness Education

Recent Publications

2026
Mycobiogenic silver nanoparticles enhance sorghum growth and salinity tolerance by modulating photosynthesis and oxidative stress responses
ZIOTTI, A. B. S.; OTTONI, C. A.; KUHL, V.; LIMA NETO, MILTON C.
Theoretical and Experimental Plant Physiology
2025
Ocean Acidification Impairs Growth and Induces Oxidative Stress in the Macroalgae Ulva fasciata and Petalonia fascia
FREITAS, F.; BARBOZA, L. V.; KUHL, V.; CASTRO, I. B.; LIMA NETO, MILTON C.
2025
Physiological and biochemical changes associated with the induction of facultative CAM in Pereskia aculeata under drought stress and recovery
CENCIARELI, LUANNA COSTA; JUSTI, MONI SOARES; DA SILVA, SERGIO LUIZ FERREIRA; DE ALMEIDA, LUIZ FERNANDO ROLIM; SERSHEN; LIMA NETO, MILTON C.
2024
The C3-CAM shift is crucial to the maintenance of the photosynthetic apparatus integrity in Pereskia aculeata under prolonged and severe drought
BARROS, J. P. A.; LIMA NETO, MILTON C.; BRITO, N. D. S.; HERMINIO, P. J.; SANTOS, H. R. B.; SIMOES, A. N.; NUNES, V. G. LIMA; SOUZA, E. S.; FERREIRA SILVA, S. L.
2023
The plasticity of the photosynthetic apparatus and antioxidant responses are critical for the dispersion of Rhizophora mangle along a salinity gradient
SILVA, BRUNO PEREIRA; SABALLO, HELOISA MARIA; LOBO, ANA KARLA MOREIRA; NETO, MILTON COSTA LIMA

Our Team

Millton Costa Lima Neto

Coordinating Professor (CNPq Researcher Level 2)

PhD in Biochemistry from UFC, MSc in Botany from UFRPE, BSc in Biological Sciences from UFPB. Postdoctoral fellowships at the University of Manchester and Federal University of Ceará. Visiting Professor at the University of Birmingham, UK and University of Kwazulu-Natal, South Africa. Investigates the impact of global climate change on the photosynthetic metabolism of plants, macroalgae, and microalgae, aiming to understand their adaptive responses and contribute to the future of food security and biotechnology.

Vitória Kühl

Master's Student (FAPESP Scholar)

Degree in Biological Sciences from IB/CLP UNESP (2024). Master's student in the Interunit Plant Biology Graduate Program at UNESP Botucatu. FAPESP Master's Scholar. Seeks to understand how the main enzymes of Crassulacean Acid Metabolism (CAM), PEPc and RuBisCO, are regulated in Agave sisalana plants under salt stress, as well as stomatal dynamics, aiming to comprehend the photosynthetic plasticity of this species facing environmental variations.

Gabriel Guimarães

Undergraduate Researcher (FAPESP Scholar)

Undergraduate in Biological Sciences at UNESP São Vicente. FAPESP Undergraduate Research Scholar. His work aims to study the memory effect induced by priming in Soybean plants under recurrent drought.

Mariana Jussiani

Undergraduate Researcher (CNPq Scholar)

Undergraduate in Biological Sciences at UNESP São Vicente. CNPq Undergraduate Research Scholar. The research investigates the use of aquaculture waste as biostimulants for macroalgae cultivation. The focus is bioremediation, using algae to absorb nutrients from effluents and transform environmental liabilities into sustainable resources for integrated systems.

Mariane Magno

Undergraduate Researcher (FAPESP Scholar)

Undergraduate in Biological Sciences at UNESP São Vicente. FAPESP Undergraduate Research Scholar. Focuses on the metabolic plasticity and physiological resilience of the Agave sisalana species under salt stress. The main objective is to investigate how salinity modulates the activity of key CAM metabolism enzymes, seeking to understand if this photosynthetic pathway operates according to the environment and the plant's developmental stage.

Laura Donato

Undergraduate Researcher

Undergraduate in Biological Sciences at UNESP São Vicente. My research line focuses on the cultivation of marine microalgae, investigating their growth, productivity, and potential for biotechnological applications such as the production of biocompounds, bioenergy, and sustainable inputs.

Beatriz Bernardes

Undergraduate Researcher (COPE Scholar)

Undergraduate in Biological Sciences at UNESP São Vicente. UNESP COPE Scholar. I seek to analyze the morphoanatomical plasticity and physiological adjustments of young Agave sp. plants facing a salinity gradient, correlating structural strategies with biomass maintenance.

Matheus Vieira

Undergraduate Researcher

Undergraduate in Biological Sciences at UNESP São Vicente. His work aims to investigate the priming effect of H2O2 in Soybean plants under recurrent drought conditions.

Guilherme Velasco

Undergraduate Researcher

Undergraduate in Biological Sciences at UNESP São Vicente. His work aims to investigate the priming effect of H2O2 in Soybean plants under recurrent drought conditions.